Advantages of translational medicine

One of the main advantages of the system is that the clinical questions can be transformed to basic research studies and after that, basic research findings can be transformed into clinical applications and shared with the various clinical/therapeutic areas quickly and effectively.

Clinical medicine should be divided into two main categories: general and translational medicine. The central work of general medicine is to provide basic care and graduate training, while translational medicine – besides the good care - engages in clinically-oriented studies (thus increasing scientific output), pharmaceutical phase trials (to discover new therapies and grow institutional income) and postgraduate training (to raise the number of PhDs and other academic degrees). Patients are only affected by translational medicine if they undertake to participate in a clinical study (based on the National Institutes of Health (NIH) model).

Another feature of the system is its multidisciplinary nature; that is, it facilitates theoretical and clinical research in particular medical specialties in coordination with various fields (IT, mathematics, clinical research, theoretical research and management).

In order to maximize the output, the main pillar of translational medicine comprises (1) the registration system, which covers all the clinical areas and is expanded through the appropriate IT communication infrastructure, and (2) the biobank which is linked to it. These systems are set up and maintained with data entered and mutually shared in accordance with strict legal and ethical principles. It is thus possible to make a sufficient number of cases available for ongoing clinical studies and provide solid evidence to better understand and treat particular diseases and to boost the scientific value of future publications.

The most outstanding centres for translational medicine, where the translational approach to medicine was first institutionalised, are the National Institutes of Health (NIH) and the Harvard Clinical and Translational Science Centre. Today, centres like these can also be found in Cambridge and Oxford. They represent the world’s greatest research potential, with studies published in the most significant scientific journals.

Since Hungary and Central Eastern Europe do not play a role in this domain yet.

The implementation of translational medicine in Hungary aims to change this situation.